By 2026, at least 1 phase 3 clinical trial shows positive results with DMT or 5-MeO-DMT for a mental disorder.

Will Deuterated N,N-Dimethyltryptamine undergo phase III trials by EOY 2027?

Will the FDA approve a psychedelic-assisted therapy for a mental disorder by 2026?

Will a drug designed with significant contribution from an AlphaFold-like system pass a Phase I trial by end of 2025?

Will an academic paper on tFUS + psychedelics be published by EOY 2025?

Will any two of marijuana, MDMA, and psilocybin be rescheduled by 2026?

Will methoxetamine (MXE) be widely available again on darknets (or any site) by EOY 2025?

FDA legalizes magic mushrooms/psilocybin/etc. for clinical use by the end of 2025

Will psilocybin be federally descheduled from a Schedule 1 illegal drug in the USA before the end of 2025?

Will an mRNA HIV vaccine pass Phase 2 trials by 2025